Radiation is one of the major problems in this situation. It can harm you and even kill you if you get too radiated. It can cause you to get chemicals in your skin and body also it can harm your brain by getting memory loss. The body can go to space if protected by something because if it goes without protection than it will be harmed and will die if too much. The body will respond to different things differently and the homeostasis of the body is trying to adopt, but after a while it will. I think that the nervous system will have a hard time going through because space has lots of bad stuff that can hurt the brain bad. The respiratory system will have to adapt to the tanks because if you tried breathing in space you won't be able to breath because space has no air. The digestive system will feel weird because you will be floating around and you might feel sick. Also the Integumentary System is probably going to be different in space because your hair gets pulled up and your skin when it sheds the little particles just float around.